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Logest

Category: Woman's Health

Description

Lynoral (Ethinyl Estradiol) is a synthetic estrogen that is used to prevent pregnancy.

Active Ingredient: Ethinylestradiol

Lynoral (Logest) as known as: Aethinyloestradiolum, Aida, Aliane, Apri, Aranelle, Arianna, Balanca, Balziva, Belara, Belarina, Bellgyn ratiopharm, Bellissima, Bellune, Bemasive, Binovum, Biviol, Brenda-35 ed, Brevinor, Careza, Carlin, Chariva, Chloe, Ciclidon, Ciclomex, Cileste, Clairette, Claudia, Clevia, Conceplan, Cryselle, Cycléane, Cyclen, Cyclessa, Cypestra-35, Cyprelle, Cyprene-35 ed, Cyprest, Cyproderm, Cyprodiol, Cypromix, Cyproteron, Cyprotérone, Cyproterone-apc, Daphne, Demulen, Desmin, Désobel, Desolett, Desorelle, Desoren, Diacare, Diane mite, Diane-35, Dianette, Dianova mite, Dileva, Diva-35, Dixi 35, Docdonna, Drina, Drosperin, Dueva, Duofem, Duoluton, Edelsin, Edulen, Efézial, Elisamylan, Elleacnelle, Elleogest, Enriqa, Ergalea, Estelle-35, Estinette, Estinyl, Estraceptin, Estrostep, Ethinyl estradiol, Ethinylestradiolum, Ethinyloestradiol, Etinilestradiol, Etinilestradiolo, Eufem, Eugynon, Evalon, Evépar, Evra, Facetix, Fedra, Felixita, Femcon, Femelle, Femhrt, Femiane, Femigen, Femina, Feminac 35, Feminil, Femodeen, Femoden, Femodene, Femodette, Femovan, Gestinyl, Gestodelle, Gestodette, Gestodiol, Gestofeme, Gestonette, Ginera, Ginette, Ginoden, Gracial, Gratiella, Gynelle, Gyneplen, Gynera, Gynofen, Gynovin, Gyselle, Harmonet, Harmonette, Holgyeme, Hormofen, Improvil, Jasminelle, Jeanine, Jenetten, Jennifer, Juliette, Kariva, Katya, Kelnor, Kipling, Lamuna, Laurina, Leena, Libeli, Liberel, Lilia, Lindynette, Linessa, Liofora, Logest, Lovelle, Low-ogestrel, Lucille, Ludeal, Lumalia, Lybella, Mamineurine, Masbell, Meliane, Melodene, Melodia, Microdiol, Microfollin, Microgestin, Midane, Milligest, Milvane, Minero, Minerva, Minesse, Minigeste, Miniphase, Ministat, Minulet, Minulette, Miravelle, Mirelle, Modina, Mona hexal, Moneva, Mononessa, Morea, Myralon, Myvlar, Necon, Nelova, Neo-eunomin, Neocon, Non-ovlon, Norimin, Norinyl, Nortrel, Norvetal, Novial, Novynette, Nuvaring, Ocella, Ogestrel, Oilezz, Ortho, Orthonett novum, Ortrel, Ovcon, Ovestin, Ovidol, Ovral, Perléane, Phaeva, Planak, Planovar, Planum, Practil 21, Pramino, Prefest, Previfem, Primosiston, Progynon c, Prosexol, Prostarin, Ratiopharmeva, Reclipsen, Reginon, Regulon, Remexin, Restovar, Securgin, Suavuret, Sunya, Sylgestrel, Sylvan, Sylvie, Syndi, Synfase, Synphase, Synphasec, Taril, Tri-gynera, Tri-legest, Tri-minulet, Tri-sprintec, Triadene, Triafemi, Tricilest, Triella, Trigynovin, Triminulet, Trimiron, Trinessa, Trinovum, Triodeen, Triodena, Triodene, Trisequens, Valette, Varnoline, Velivet, Visofid, Vivelle, Vreya, Xylia, Yadine, Yarina, Yasminelle, Yax, Yaz, Yira, Yris, Zenchent, Zovia, Zyrona

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The list with possible interactions is so complicated that it should be interpreted by professionals only.

Logest Online

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Logest Logest

Drug name: Brand Logest

Active substance: Ethinyl estradiol, Gestodene

Pharmacological effects: Logest is a combined preparation the effect of which is associated with the active ingredients included in the drug. The contraceptive effect of the preparation is achieved due to the following therapeutic mechanisms:

  • Prevention of ovule formation
  • Decreased responsiveness of the endometrium to the embryonic sac
  • Increased viscosity of the cervical mucous

Logest also exerts specific beneficial effects:

  • Normalization of the menstrual cycle
  • Prevents certain gynecological disease including tumor formation

Indications: The drug is indicated as a contraceptive but also may be used after a thorough consultation with your health care provider for treatment of functional changes in the menstrual cycle.

Warnings and Precautions: The drugs should not be used in the following conditions:

  • Hypersensitivity to any components of the preparations.
  • Liver failure
  • Liver tumors
  • Thromboembolia
  • Inborn hyperbilirubinemia
  • Cerebral blood flow dysfunctions
  • Ischemic heart disease
  • Arterial hypertension
  • Atherosclerosis
  • Myocarditis
  • Diabetes
  • Retinopathy
  • Angiopathia
  • Cardiac malformation
  • Anemia
  • Hormone dependent cancer of the mammary gland or of the endometrium
  • Lipid metabolism dysfunctions
  • Idiopathic jaundice, skin itching before pregnancy
  • Inflammatory disease of the womens urogenital tract
  • Otosclerosis
  • Epilepsy
  • Porphyry
  • Pregnancy
  • Lactation period
  • Patients after 35 years of age
  • Predisposition to uterine bleeding
  • Hyperfollicular climax stage

Side effects: Drugs may cause side-effects which in specific patients may manifest differently. In the following paragraph we want to underline the most serious and frequent side effect of Logest that were identified by the drug manufacturers. The possibility of the adverse effect manifestation depends only on the individual and his specific traits. Logest side effects include:

  • Gastro-intestinal tract: gastralgia, nausea, vomiting, jaundice, hepatocellular adenoma
  • Endocrine system: breast engorgement, increased body weight, decreased libido, polymenorrhea
  • CNS: headache, mood changes
  • Cardiovascular system: thrombophlebitis, thromboembolia
  • Sensory organs: vision impairment, decreased hearing
  • Allergic reactions
  • Others: generalized itching, bleeding, chloasma, Na+ and Ca2+ metabolism changes

For full information on any risks and adverse effects associated with Logest. please consult your doctor, read the included leaflet or contact our customer support service.

Interactions: Before using Logest please tell your doctor which drugs or supplements you are already taking including those bought without a prescription. Also check if any additional medicine which you will take during the course of Logest therapy are safe in combination. Especially mention if you are taking the following groups of drugs:

  • Antiepileptics
  • Steroid hormones
  • Antibiotics
  • Diabetes treatment

Patients information: Logest is not to be shared with healthy individuals. It is strictly FORBIDDEN to use the drugs in treatment of any conditions unrelated to their indications. The product as well as utilized vials, syringes, needles if used during the course of treatment should be kept out of reach of children and never reused.

Other articles

Logest - instructions for use, indications, dosage

Logest

Logest - monophasic combined progestogen-estrogen contraceptive.

Release form and composition

Logest issued in the form of dragees and film-coated tablets: round, white (21 pieces in blister, 1 or 3 blisters in a carton box.).

The active substances (1 tablet / pellet)

  • Gestodene - 75 g;
  • Ethinyl estradiol - 20 micrograms.

Auxiliary ingredients: corn starch, polyvidone 700,000, sucrose, calcium carbonate, 25000 polyvidone, talc, Macrogol 6000, magnesium stearate, wax mountain glycol, lactose monohydrate.

Indications

Logest used for contraception.

Contraindications

The following diseases and conditions are absolute contraindications to the drug; if any of them develop in the first period of application Logest, contraceptive should be discontinued:

  • Arterial and venous thrombosis, including a history (e.g. myocardial infarction, pulmonary artery branches thromboembolism, deep vein thrombosis of the lower extremities, cerebrovascular disease);
  • State prior thrombosis, including a history (e.g. angina, or transient ischemic attack);
  • Have expressed and / or multiple risk factors for thrombosis;
  • Severe liver disease or hepatic impairment (before normalization of liver function tests);
  • Liver tumors (both malignant and benign), including the anamnesis;
  • Pancreatitis from severe hypertriglyceridemia, including the anamnesis;
  • Diabetes mellitus with vascular complications;
  • Migraine with focal neurological symptoms, including the anamnesis;
  • Established or suspected hormone-dependent malignancies;
  • Vaginal bleeding of unknown origin;
  • Pregnancy or the suspicion of it;
  • Lactation;
  • Hypersensitivity to the drug.

In the following cases Logest may be appointed only after an assessment of the expected benefits of oral contraceptives and the potential risks:

  • The presence of risk factors that can lead to thrombosis or embolism, such as smoking, predisposition (presence of someone from the next of kin at the young age of thrombosis, cerebrovascular accident or myocardial infarction), obesity, diseases of the heart valves, arterial hypertension, disorders heart rate, migraine without focal neurological symptoms, dislipoproteinemia, major trauma, major surgery, prolonged immobilization;
  • The presence of other diseases in which the possible violation of the peripheral circulation, such as phlebitis of superficial veins, ulcerative colitis, Crohn's disease, hemolytic uremic syndrome, sickle cell anemia, systemic lupus erythematosus, diabetes without vascular complications;
  • liver disease;
  • hypertriglyceridemia;
  • Hereditary angioedema;
  • Diseases that have arisen for the first time or worsened during a previous pregnancy or as a result of previous use of sex hormones (such as Sydenham's chorea, otosclerosis with hearing impairment, cholestasis, porphyria, jaundice, gallbladder disease, herpes, pregnancy).
Dosage and Administration

The tablets / pills taken orally by 1 piece. per day according to the above procedure on the package, at one and the same time of day, with a small amount of water, for 21 days. Then make a standard 7-day break, during which time (usually 2-3 days after the last tablet) develops withdrawal bleeding, which is before the start of the new packaging can not end.

Terms of the beginning of reception, depending on the circumstances:

  • Absence of the previous month of any hormonal contraceptive: 1-day menstrual cycle. You can start using the product, and 2-5 days of menstrual bleeding, but then during the first 7 days is necessary to additionally use a barrier method of contraception;
  • Switching from another combined oral contraceptive: optimally - the next day after taking the last gormonosoderzhaschey tablets, but not later than the end of the 7-day break (when using the drug, calculated on a 21-day course) or the next day after the last inactive tablet (with the use of the drug. calculated on a 28-day course);
  • Switching from contraceptive patch or vaginal ring: the day of the removal of the patch or the ring, but no later than the day on which should be pasted a new patch or put a new ring;
  • Switching from contraceptive containing a progestogen only mini-pill - in any day without a break; implant or intrauterine releasing progestogen (Mirena) - on the day of its removal; injectable form - on the day when the next infection should be done. In all cases, during the first 7 days of Logest need to use an additional barrier contraceptive;
  • Abortion in the I trimester of pregnancy: the day of surgery, then additional contraceptive protection is not required;
  • Abortion in the II trimester or childbirth: 21-28 on the day. If the reception is started later in the week requires an additional barrier method of contraception. If in this interval there was a sexual contact, it is recommended to wait until the first menstruation or exclude pregnancy before you start taking Logest.

In the case of missing the next tablets / pills to take the drug should be as soon as possible, to continue to take a set time. Thus, in one day can be received 2 tablets / pills. If from the moment of admission did not go more than 12 hours, contraceptive efficacy of the drug is not reduced. If it has been more than 12 hours and the drug efficacy may be reduced, so for 7 days is recommended to use an additional barrier method of contraception. If the package is left in less than 7 tablets / pills, start the next pack should be without interruption. The more missed tablets and the closer to the pass 7-day break, the greater the chance of pregnancy.

In the case of vomiting and diarrhea, the woman should be guided by instructions on the passage of the next administration.

Changing days beginning menstrualnopodobnoe bleeding:

  • To delay menstruation, you should continue taking the drug from a new package without the usual 7-day break. The tablets / pills from a new package can be taken for as long as is necessary (until the package is finished). In this case, the possible spotting or breakthrough uterine bleeding. Reactivate the reception of the new packaging is necessary after the usual break;
  • To move the start of menstruation to another day of the week, should be cut a break in reception for as many days, as many as needed. However, it should be borne in mind, the shorter the interval, the higher the risk of withdrawal bleeding, as well as the occurrence of breakthrough bleeding or spotting during the reception of the second package of the drug.
Side effects

When receiving Logest possible irregular bleeding (breakthrough and spotting), especially in the first few months of taking the drug.

cases of other side effects are also known. Their relationship with the combined oral contraceptive has not been confirmed, but not refuted:

  • Authority of: rare (<1/1000) - contact lens intolerance (discomfort when wearing them);
  • Gastrointestinal tract: often (> 1/100) - abdominal pain, nausea; uncommon (> 1/1000 and <1/100) - vomiting, diarrhea;
  • Nervous system: often - headache; rarely - headache;
  • Psychiatric disorders: common - reducing or mood swings; infrequently - decreased libido; rarely - increased libido;
  • Reproductive system and breasts: often - pain and breast engorgement; infrequently - hypertrophy of the breast; rarely - discharge from the breasts, vaginal discharge;
  • Immune system: rarely - hypersensitivity;
  • Metabolism: Infrequent - fluid retention;
  • Skin and subcutaneous tissue disorders: rare - rash, hives; rarely - erythema nodosum and multiforme;
  • Other: often - increase in body weight; rarely - weight loss.

Possible serious side effects in women taking combined oral contraceptives:

  • Cerebrovascular disorders;
  • Arterial and venous thromboembolic disorders;
  • Increased blood pressure;
  • Violation of the functional parameters of the liver;
  • Liver tumors (benign or malignant);
  • Changes in glucose tolerance or effect on peripheral insulin resistance;
  • chloasma;
  • Hypertriglyceridemia.

Also known rare cases of development or deterioration, whose connection with the use of oral contraceptives has not been proven:

  • Herpes pregnant;
  • Cervical cancer;
  • Porphyrin disease;
  • The formation of gallstones;
  • Chorea;
  • Hemolytic-uremic syndrome;
  • Ulcerative colitis;
  • Crohn's disease;
  • Systemic lupus erythematosus;
  • Hearing loss associated with otosclerosis;
  • Jaundice and / or itching associated with cholestasis.
special instructions

Before the appointment Logest as any other hormonal contraceptives, a woman should exclude pregnancy and disorders of blood clotting process undergo a full medical (including a study of personal and family history, blood pressure, body mass index) and gynecological examination (including cytology smear cervical and breast examination). Follow-up examinations are recommended every six months 1.

Patients who are prescribed oral contraceptive, should be warned that these drugs do not protect against HIV infection and other diseases, sexually transmitted diseases.

If during the 7-day break in taking the drug is not menstrualnopodobnoe bleeding, should not receive renewing Logest, conduct patient examinations.

Due to the increased risk of thrombosis should stop taking the drug for 6 weeks prior to elective surgery and can resume no earlier than 2 weeks.

Patients who are prone to the development of chloasma, during the period of application Logest advised to avoid sun exposure.

Women taking oral contraceptive should be appreciated that the drug may influence the course of the menstrual cycle, the properties of cervical mucus and rectal temperature.

In the case of the onset of symptoms, which may indicate the development of thrombosis or thromboembolism (swelling of extremities, and pain in the legs in the course of the veins, acute pain, feelings of heaviness or constriction in the chest, sudden shortness of breath) should stop taking Logest and conduct a survey.

Cancel the preparation and conduct additional inspections as necessary in the event of severe pain in the abdomen, constant itching, severe depression, severe headaches and migraines, as well as with frequent seizures, a significant increase in blood pressure, sudden changes in speech, hearing or vision.

In case of appointment of drugs that reduce the contraceptive effect Logest, during the whole period of treatment and for 7 days after the end (in the case of rifampicin - 4 weeks) you should use additional methods of contraception.

Drug interactions

The interaction of oral contraceptives with other drugs may cause breakthrough bleeding or a decrease in contraceptive effectiveness.

Drugs that induce hepatic microsomal enzymes which may enhance the clearance of hormones. These include barbiturates, rifampicin, primidone, phenytoin, carbamazepine. A similar reaction is expected to be available, while the use of drugs St. John's wort, topiramate, griseofulvin, oxcarbazepine, felbamate. At the time of their admission and 28 days after treatment you should use an additional barrier method of contraception.

HIV protease (for example Ritonavir), non-nucleoside reverse transcriptase inhibitors (including nevirapine), and combinations thereof may also potentially affect hepatic metabolism.

Some antibiotics (such as tetracyclines and penicillins) may reduce the concentration of ethinyl estradiol - one of the active substances Logest. For this reason, during the use of antibiotics and for 7 days after their withdrawal is necessary to use an additional barrier method of contraception. If the period of use of barrier contraceptives ends later than tablets / pills in the package, the new package should pass without the usual 7-day break at the reception.

Like all combined oral contraceptives Logest may affect the metabolism of any other simultaneously used drugs that can lead both to decrease (eg lamotrigine) and increase (e.g. cyclosporine) concentrations in plasma and tissues.

Terms and conditions of storage

Store in a dark, place inaccessible to children at temperature not exceeding 25 ° C.

The shelf life of tablets - 3 years, dragees - 4 years.

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Logest tabl

Logest tabl. #21

Description for Logest #21

Pharmacological Effects:
Low-dose monophasic oral contraceptive with antiMKS and antiandrogenic effects. The contraceptive effect is due to several factors, most important of which is inhibition of ovulation and change the viscosity of cervical mucus. Endometrium remains unprepared for the implantation of the egg. As a result of increasing the viscosity of cervical mucus penetration of sperm cells is hampered in the uterine cavity. Drospirenone has antiMKS activity that can prevent weight gain and other symptoms associated with fluid retention (delay prevents Na +, caused by estrogen provides a very good tolerability and positive impact in premenstrual syndrome). In combination with ethinylestradiol improves the lipid profile and increases the concentration of HDL. Has anti-androgenic activity, which leads to a decrease acne formation and reduced production of the sebaceous glands, has no effect on ethinylestradiol induced increase in education globulin, sex hormone binding (inactivation of endogenous androgens). Drospirenone devoid of any androgenic, estrogenic, SCS and antiGKS activity. This, coupled with antiMKS and antiandrogenic effects, drospirenone provides biochemical and pharmacological profile similar to natural progesterone. As with all combined oral contraceptives has a positive effect Noncontraceptive: menstrual bleeding becomes lighter and shorter, which reduces the risk of anemia, pain - less pronounced or disappear completely.


Indications:
Contraception (prevention of unwanted pregnancy).

Appointment of a combined contraceptive with antimineralokortikoidnymi and antiandrogenic properties (Yasmin) may be particularly useful for women with hormone-dependent fluid retention, as well as women with acne (acne) and seborrhea.


How to use:
Oral, 1 tablet, in order listed on the packaging, every day at about the same time with a little water, continuously for 21 days. Acceptance of each of the following package starts after a 7-day break, during which there is bleed bleeding. It usually begins 2-3 days of taking the last tablet and may not end before starting a new package. In the absence of taking any hormonal contraceptive in the previous month, the drug begins on the first day of the menstrual cycle (first day of menstrual bleeding). Allowed to start taking on the 2-5 day of menstrual cycle, but in this case it is recommended to additionally use a barrier method of contraception during the first 7 days of pills from the first package. In the transition from receiving other COCs preferably start taking the drug on the day after taking the last active tablet from the previous packaging, but not later than the day after the usual 7-day break in reception (for products containing 21 tablets), or after the last inactive tablets (for products containing 28 tablets per pack). In the transition from contraceptives containing only progestogens (mini-pill, injectable form, the implant): a mini-pill you can go to any day (no break), with the implant - the day of his removal from the injection form - from the day when must had to be done following an injection. In all cases, you must additionally use a barrier method of contraception during the first 7 days of tablet. After the abortion I trimester of pregnancy can start taking immediately. Subject to this condition, there is no need for additional contraceptive protection. After childbirth or abortion in the II trimester of pregnancy is recommended to start taking the drug for 21-28 days. If the reception is started later, it is necessary to additionally use a barrier method of contraception during the first 7 days of tablet. In the case of sexual intercourse prior to taking the drug should be ruled out pregnancy, or must wait for the first menstruation.Receiving missed pills: the delay in pill was less than 12 hours, contraceptive protection is not reduced. Need to take a pill as soon as possible, should be taken at the usual time. If the delay in the pill was more than 12 h (interval since last pill taking more than 36 h), contraceptive protection may be reduced. In case of missing 1-2 weeks of taking the drug should take the last missed tablet as soon as possible (even if it means taking 2 tablets at a time). Take the next pill at the usual time. Must additionally be used a barrier method of contraception for the next 7 days. If intercourse took place within 1 week before the missed pills, you must consider the likelihood of pregnancy. The more pills missed and the closer this pass to the 7-day break in taking the drug, the greater the risk of pregnancy. In case of missing 3 weeks of medication, you should take the last missed tablet as soon as possible (even if it means taking 2 tablets at a time). Take the next pill at the usual time. Must additionally be used a barrier method of contraception for the next 7 days. In addition, the pill from the new pack should be started once the current package, ie without interruption. Most likely, the hemorrhage "undo" will not be until the end of the second pack, but can be observed "smearing" spotting or uterine bleeding "cancel" in the days of the drug from the second pack. In case of missing a pill and a lack of the first free medication interval bleeding "undo" is necessary to exclude pregnancy. In the case of missed doses can be guided by the following two basic rules: the drug should never be interrupted by more than 7 days and 7 days of continuous tablets needed to achieve adequate suppression of the hypothalamic-pituitary-ovarian system. If vomiting occurs within 3-4 hours after taking the pill absorption may be incomplete. In this case, you must observe the rules of the drug in case of missing pills. If the patient does not want to change the normal administration of the drug, it should adopt, if necessary additional tablet (or several tablets) from other packages. To postpone the date of onset of menstruation is necessary to continue taking pills from a new package immediately after taken all the tablets from the previous one, without a break in the reception. Tablets from a new package can take up to a maximum until packaging is completed. In patients receiving the drug from the second pack can be marked "smearing" bleeding from the vagina or uterine bleeding "breakthrough." Resume taking the drug from a new package follows the usual 7-day break. To transfer the date of onset of menstruation at the other day of the week should be shortened next break in the pill for as many days, how much you want to move the onset of menstruation. The shorter the interval, the higher the risk of bleeding "cancel" in the future, "smearing" selections and "breakthrough" bleeding during the second pack (just as in the case of delay the onset of menstruation).


Side effects:
The following undesirable effects have been described in women taking Yasmin, and their relationship with the drug was neither confirmed nor refuted: breast tenderness, discharge from the breasts, headache, migraine, changes in libido, depressed mood, poor tolerance of contact lenses, nausea. vomiting, changes in vaginal secretion, various skin disorders, fluid retention, weight change, hypersensitivity reactions.

Sometimes it can develop chloasma, especially in women with a history of chloasma during pregnancy.


Contraindications:
Yasmin should not be used if any of the states listed below. If any of these conditions develop for the first time while taking the drug should be immediately repealed.

The presence of thrombosis (venous and arterial) present or in history (eg deep vein thrombosis, pulmonary embolism, myocardial infarction, cerebrovascular disorders).
The presence of current or a history of states prior to thrombosis (eg transient ischemic attack, angina).
Diabetes mellitus with vascular complications.
The presence of severe or multiple risk factors for venous or arterial thrombosis may also be regarded as a contraindication.
The presence of current or a history of severe liver disease (as long as liver tests do not come back to normal).
Severe renal insufficiency or acute renal failure.
The presence of current or a history of liver tumors (benign or malignant).
Identified hormone-malignant diseases of genital organs or breasts or suspicion on them.
Vaginal bleeding of unknown origin.
Pregnancy or suspicion of it.
Breastfeeding.
Hypersensitivity to any component of Yasmin.


Pregnancy:
The drug is prohibited during pregnancy and lactation!


Interaction with other drugs:
Drug interactions that result in increased clearance of sex hormones, may lead to breakthrough bleeding or a reduction of contraceptive reliability. It has been established in respect of hydantoin, barbiturates, primidone, carbamazepine and rifampicin; also have assumptions regarding oxcarbazepine, topiramate, felbamate and griseofulvin. The mechanism of this interaction is based on changes of liver enzymes. Maximum enzyme induction is not usually seen within 2-3 weeks, but may then be stored for at least 4 weeks after cessation of drug therapy.

Contraceptive protection is reduced when antibiotics such as ampicillin and tetracyclines. The mechanism of this action is not clear.

Women receiving any of the above classes of drugs a short course in addition to Yarin should temporarily use a barrier method of contraception during concomitant medication, and within 7 days after their cancellation. During the reception, rifampin, and within 28 days after its cancellation, in addition to Yarin should use a barrier method of contraception (eg condoms). If concomitant use of the drug started at the end of reception packages Yasmin, Yasmin next pack should be started without the usual break in reception.

In women, a long time receiving drugs affecting liver enzymes, it is necessary to consider other methods of contraception.

There is a theoretical possibility of increasing serum potassium levels in women receiving Yasmin simultaneously with other drugs that may increase serum potassium levels. These medications include ACE inhibitors (angiotensin-converting enzyme) receptor antagonists, angiotensin-II, some anti-inflammatory drugs (eg indomethacin), potassium-sparing diuretics and aldosterone antagonists. However, studies evaluating the interaction of an ACE inhibitor with a combination of drospirenone / estradiol in women with mild hypertension, found no significant difference between serum potassium concentration in women treated with enalapril compared with placebo.

Effect on lab tests

Acceptance of sex steroids may affect the biochemical parameters of liver function, thyroid gland, adrenal glands and kidneys, as well as levels of transport of plasma proteins, such as kortikosteroidsvyazyvayuschy globulin and lipid / lipoprotein fractions, carbohydrate metabolism, coagulation and fibrinolysis. Changes usually occur within laboratory norms. Because of its activity antimineralokortikoidnoy drospirenone increases the activity of renin and aldosterone plasma.


Overdose:
On the serious side effects of overdose were reported. Symptoms that may occur in this case: nausea, vomiting and slight vaginal bleeding. There is no specific antidote, should be treated symptomatically.


Product:
Film-coated tablets for oral administration.
Cycle pack containing 21 tablets.


Storage Conditions:
Shelf life - 3 years.
You can not use after expiry date!
Keep out of reach of children!
Available on prescription.


Ingredients:
Each tablet, film coated contains.
Active ingredients: 3 mg of drospirenone, ethinyl estradiol 0.03 mg.
Excipients: lactose monohydrate, corn starch, modified starch (pregelatinized starch), polyvidone 25000, magnesium stearate, hydroxypropyl methylcellulose, macrogol 6000, talc, titanium dioxide, yellow iron oxide.


Extras:
If any of the conditions / risk factors listed below are currently available, it should carefully weigh the potential risks and expected benefits of the treatment Yasmin in each individual case and discuss it with the woman before she decides to start taking the drug. In the case of aggravation, amplification, or the first manifestation of any of these conditions or risk factors, the woman should consult with their physician, who may decide to repeal the drug.


Diseases of the cardiovascular system
Several epidemiological studies showed a slight increase in the incidence of venous and arterial thrombosis and thromboembolism in COC.

Venous thromboembolism (VTE), manifested in the form of deep vein thrombosis and / or pulmonary thromboembolism may develop during use of combined oral contraceptives. The approximate incidence of VTE in women taking oral contraceptives with low-dose estrogen (<50 mcg ethinyl estradiol) is up to 4 per 10 000 women per year compared with 0,5-3 per 10000 women per year to women not using OK. However, the incidence of VTE developing in COC is less than the frequency associated with pregnancy (6 per 10,000 pregnant women per year).
In women taking combined oral contraceptives, are described extremely rare cases, thrombosis of other blood vessels, such as hepatic, mesenteric, renal arteries and veins, central retinal vein and its branches. Communication with COC has not been proved.

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Logest or ZHanin? Страница 2

And more: whether there is at these preparations an international name?
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Precisely I know, that abroad Logest name Meliane (tried to buy on Malta, in Spain and France).
[/QUOTE]


I to the USA, but all the same thanks.

The Saw logest. To me the doctor in the categorical form has told or said to pass to it or him as on nizkodozirovannyj (before accepted Triregol. Did or made breaks during which the organism worked as hours). Here has solved a break in reception logesta in the summer to make. Four months was not monthly, the organism and could not come to itself, has handed over analyses on hormones, I am now flied or treated.


And my doctor has told or said. That after reception logesta at many delays for 2-3 months happen. So if there is an opportunity better preliminary to hand over the analysis on hormones, and then already to appoint or nominate OK.
[/QUOTE]

At me similar history. Saw Marvelon, has then passed on -35. After the termination or discontinuance of reception of last preparation the cycle was broke or disturbed. A menses of times in two months, poor or scanty, last two times there were enough linings on every day. The doctor in Russia has advised to begin reception of preparations (as I already wrote, on a choice) for normalization of a cycle. From analyses there was only a general or common smear, and that, the preparation was appointed or nominated before reception of result. Unfortunately, there was no time for searches of other doctor. Then I have left, and now I can not address to the doctor, yet there will be no insurance. I wish to make the analysis of a hormonal background as soon as there will be an opportunity. Perhaps, it was necessary to listen to the doctor and to begin reception of tablets - a cycle walks, but I am afraid, that it will not affect or not have an effect restoration of my native cycle (if there are disturbances) in any way, i.e. I shall eliminate or erase;remove not a problem, and its or her consequences. At whom what references? If there is someone from the USA, tell, what preparations here are popular.

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