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Drugs For Enhancing Brain Functional Capacity

Ricky Hussey

Drugs For Enhancing Brain Functional Capacity

Cerebral Activators (Cognition Enhancers) While the use of CNS stimulants has declined due to non-specific nature of their actions, a new class of drugs called 'Cerebral Activators' has been introduced. It is claimed that these drugs improve the brain functions particularly in dementia - a condition of brain characterized by loss of intellect and memory, and may have a role in the treatment of Alzheimer's disease. However their use is limited and the claims regarding their efficacy are not always fully substantiated.

Piracetam (Normabrain, Neurocetam, Nootropil) This drug is supposed to directly improve the efficiency of the higher functions of the brain such as learning, memory, thought, and consciousness, both in normal and deficient situations. It does not have a sedative or psychostimulant effect. These changes are brought about by increase in nerve-to-nerve message activity and energy supply to nerve or those parts of brain which are involved in learning and memory. It variably improves brain function in senile dementia and mental retardation in children. The drug should be taken with caution in kidney or liver disease, and during pregnancy. Dosage: The recommended dose for adults is 800 mg, three times a day and for children, it is 50 mg/kg of body weight in 3 divided doses. Pyritinol (Encephabol) This improves disturbed cerebral metabolism and activates glucose metabolism. It also improves cerebral micro-circulation. It has been tried in cerebro-vascular accidents, disturbed cerebral development in children and adolescents, in post-anaesthetic recovery, and alcohol withdrawal state. Its efficacy is doubtfu1.The prescribed dose is 200 mg, three times a day for 6 to 8 weeks. Adverse Effects: It may cause disturbances, increased excitability, loss of appetite, headache, tiredness, nausea, vomiting, and diarrhoea. Other Drugs Other drugs of this group are dihydroergotoxine which is used in loss of memory, nimodipine which is useful in subarchnoid haemorrhage, nicergoline (SERMION), glutamic acid and piribedil. Ginkocer (Ginkocer, Bilovas) This is a dried extract of Ginkgo biloba. Besides bringing about some action like piracetam and pyritinol, the drug causes inhibition of the platelet-activating factor. It has been tried in the treatment of multi-infarct dementia (repeated minor strokes lead to dementia) because it improves blood supply in small brain vessels in the stroke area. Alzheimer's Disease Alzheimer's disease is a condition that occurs when there is a breakdown in the brain, in particular when there is a loss of communication among brain cells. Clear communication among brain cells is vital for the brain to function properly. If brain's networking capabilities deteriorate, cognitive skills (ability to think, reason and remember) are affected or lost. Rivastigmine (Exelon) This drug increases levels of a chemical (Acetylcholine) which is needed for nerve to nerve message transfer in the brain. It has strown improvement of brain function in Alzheimer's disease. Cognition, apathy, delusions and hallucinations improve with its use. Its usual doses is 1.5 to 3 mg twice a day. Donepezil (Donecept) It also improves cognitive functions by increasing acetylcholine levels in remaining nerves in the brains of Alzheimer's patient. It has a longer duration of action, so it is given once in 5 to 10 mg daily at night. Other Drugs Other drugs tried are Tacrine, galantamine and antioxidant vitamins (vitamin E, C). Interestingly . Ibuprofen a pain reliever has been shown to slow the course of disease. A new class of pain relievers (COX-2 inhibitors) are also being evaluated to treat this otherwise incurable disease.

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BUY PIRACETAM ONLINE Also known as Nootropil
Mental Disorders
Brand(s): Neurocetam
Manufacturer: Micro Labs

Piracetam (Nootropil) - neuroprotective drug, which directly improves the function performed by the brain. The drug has effects on the central nervous system in different ways: modify neurotransmission in the brain, improves metabolic conditions promoting neuronal plasticity, improves by acting on the rheological characteristics of blood and causing vasodilation.

Read this before you buy Piracetam online:
Indications of Piracetam: Symptomatic treatment of memory disorders, intellectual disorders in the absence of a dementia diagnosis. Piracetam has the ability to reduce the symptoms of cortical myoclonus in susceptible patients. For determining sensitivity to a specific case piracetam can be conducted trial treatment.

Long or short use of piracetam in patients with cerebral dysfunction increases concentration and improves cognitive function, as manifested by significant changes in the EEG.

Note this before you buy Piracetam online:
The drug helps restore cognitive abilities after various cerebral damage due to hypoxia, intoxication, or electroconvulsive therapy. Piracetam is indicated for the treatment of cortical myoclonus, both as monotherapy and as part of combination therapy.
It reduces the duration of the vestibular neyronita provoked.

Piracetam increased inhibits aggregation of activated platelets and, in the case of pathological rigidity erythrocyte deformability and improves their ability to filtration.

Pregnancy and breast-feeding:
Preclinical studies have shown a direct or indirect impact on pregnancy, embryonal / fetal development, birth or postnatal development.
Controlled studies of the drug during pregnancy have not been conducted. Piracetam crosses the placental barrier and into breast milk. The concentration of the drug in infants up to 70-90% of its concentration in the blood of the mother. Piracetam should not be administered during pregnancy.

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Side effects:
From the blood and lymphatic system: Hemorrhagic disorder.
Immune system: anaphylactoid reactions, hypersensitivity.
Metabolic and Nutritional Disorders: weight gain (1.29%).
On the part of the psyche: excitement, nervousness (1.13%), anxiety, depression (0.83%), hallucinations, confusion, drowsiness (0.96%).
From the nervous system: hyperkinesis (1.72%), ataxia, imbalance, exacerbation of epilepsy, headache, insomnia, fatigue (0.23%), tremor.
From the digestive system: nausea, vomiting, diarrhea, abdominal pain (including stomachalgia).
From the hearing: vertigo.
For the skin: dermatitis, pruritus, urticaria, angioedema.
Reproductive system: increased sexual desire.

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1 Why Is it Used ? PIRACETAM :

Adult: PO Adjunct in treatment of cortical myoclonus 7.2 g/day in 2-3 divided doses, increase if needed. Max: 20 g/day. Cognitive enhancer 2.4 g/day in 2-3 divided doses. Severe: Up to 4.8 g/day. IV/IM Cognitive enhancer 1-2 g 3 times/day.

2 What are the Side Effects ? PIRACETAM :

Hyperkinesia, nervousness, depression, diarrhoea, rashes. CNS stimulation, sleep disturbances, dizziness, excitement, insomnia, somnolence, wt gain.

3 What Precautions should be taken ? PIRACETAM :

Avoid abrupt withdrawal. Impaired renal function. Cardiac disorders. Haemostatic disorders. Patients who have recently undergone major surgery. Elderly.

4 Do not take this if you have any of the below. PIRACETAM :

Hepatic and severe renal impairment. Cerebral haemorrhage. Pregnancy and lactation.

5 Interaction with other medicines.

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    This medication may increase your potassium levels, or Neurocetam overdose amount mg. The most obvious systems that interact with muscular, or Piracetam 100 half life. Specifically, Neurocetam confusion side effect, like many other psychiatric medications, the FDA states that Strattera 'may increase thoughts of suicide or suicide attempts in children and teens,' and that parents should call their child's doctor if their child has: new or increased thoughts of suicide changes in mood or behavior including becoming irritable or anxious This warning doesn't mean that your child can't be prescribed Strattera or that he should stop taking Strattera if it is doing a good job managing his ADHD symptoms and not causing side effects. It has no direct effect on the muscle, does Piracetam cause incontinence. Tramadol can cause drowsiness, taking Neurocetam and geodon together, dizziness and blurred vision and this can be increased by alcohol or by taking drugs used to treat depression. Strattera dosage: 25 Mg/1 In The Evening and borderline personality disorder and the use of seroquel. Trouble focusing, sleeping pills like Piracetam, making decisions, or remembering things. Contact your doctor if this medicine seems to stop working as well in treating your symptoms. The following symptoms have been reported with Strattera: anxiety, does it burn when you snort Neurocetam, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia (psychomotor restlessness), hypomania and mania. The most important psychopathological phenomena include thought echo; thought insertion or withdrawal; thought broadcasting; delusional perception and delusions of control; influence or passivity; hallucinatory voices commenting or discussing the patient in the third person; thought disorders and negative symptoms and Piracetam prices pharmacies.

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