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Naprox

Category: Pain Relief

Description

Aleve is used to treat pain or inflammation caused by conditions such as arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps.

Active Ingredient: Naproxen

Aleve (Naprox) as known as: Adin, Aflamax, Aflaxil, Alacetan, Alidase, Aliviomas, Alpoxen, Ameproxen, Anaflex, Anapran, Anaprox, Antalgin, Apo-napro-na, Apo-naproxen, Apo-naproxeno, Apraljin, Apranax, Apraxin, Aprol, Apromed, Apron-f, Apronax, Aprowell, Aproxil, Armanaks, Arnex, Artagen, Assonax, Atac, Atren, Boloxen, Bonmin, Bonyl, Brixonax, Bruproxen, Celonax, Colfem, Congex, Coniprox, Crysanal, Cudeprox, Dafloxen, Debril, Denaxpren, Desinflam, Deucoval, Diferbest, Difortan, Diproxen, Dolaxen, Dolofen, Dolomes, Dolormin, Doprox, Dysmenalgit, Ec-naprosyn, Emox, Emoxen, Eox, Equiproxen, Eurogesic, Fabralgina, Fadalivio, Febrax, Femme, Flanax, Flaxvan, Flogen, Floginax, Flogotone, Fluconazinn, Gerinap, Gynestrel, Inflamax, Inveoxel, Inza, Iraxen, Karoksen, Laser, Lexinax, Lundiran, Mafidol compuesto, Maxiflam, Mednap, Melgar, Merck-naproxen, Messelxen, Miranax, Mobilat, Momen, Momendol, Monarit, Monochroton, Nafasol, Naflapen, Naixan, Naksetol, Naledyn, Nalgesin, Napflam, Napium, Napmel, Naponal, Naposin, Napoxpharma, Napradol, Napratec, Naprelan, Napren, Naprius, Napro, Napro itedal, Napro-a, Naprobene, Naprocet, Naprocid, Naprodev, Naprofidex, Naproflam, Naprogen, Naprogesic, Naproksen, Napromed, Naprometin, Napromex, Naprontag, Naprorex, Naproson, Naprosyne, Naprovite, Naprox, Naprox-c, Naproxennatrium, Naproxeno, Naproxenum, Naproxi, Naprozen, Naprux, Naprux gesic, Napsod, Napsyn, Napton, Narocin, Naton, Natrax, Naxdom, Naxen, Naxin, Naxo, Naxyn, Neoeblimon, Neoflam, Neoprox, Nervogesic, Neuralprona, Nitens, Noflam, Noflam-n, Nopain, Novaxen, Novo-naprox, Novo-naprox sodium, Noxen, Nu-naprox, Nuprafen, Nurolasts, Nycopren, Odontogesic, Opraks, Pabi-naproxen, Painflex, Paraflaxan, Pms-naproxen, Point, Prevacid naprapac, Prexan, Priaxen, Prodexin, Pronaxen, Pronaxil, Pronol, Proxagol, Proxen, Proxidol, Releve, Reuxen, Saprox, Seladin, Servinaprox, Sindolan, Soden, Sonafalm, Sonap, Soproxen, Supofebril, Synalgo, Synax, Syndol, Synflex, Tacron, Tandax, Tarproxen, Ticoflex, Treximet, Triox, Tundra, Uniflam, Uninapro, Vimovo, Xenapro, Xenifar, Xenobid, Xpro

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COMPU NAPROXEN 250

PROPRIETARY NAME
(and dosage form):

COMPU NAPROXEN 250

COMPOSITION:
250 mg Naproxen per tablet.

PHARMACOLOGICAL CLASSIFICATION:
A 3.1 Antirheumatics (anti-inflammatory agents).

PHARMACOLOGICAL ACTION:
COMPU NAPROXEN 250 has anti-inflammatory, antipyretic and analgesic properties. It inhibits prostaglandin synthetase.

INDICATIONS:
Schedule 3
COMPU NAPROXEN 250 is indicated for the treatment of rheumatoid arthritis, (including juvenile rheumatoid arthritis), osteoarthrosis (degenerative arthritis), ankylosing spondylitis, gout, acute musculoskeletal disorders (such as sprains and strains, direct trauma, lumbosacral pain, cervical spondylitis, tenosynovitis and fibrositis) and dysmenorrhoea.

Schedule 2
Emergency treatment of acute gout attacks. Treatment of post traumatic conditions such as pain, swelling and inflammation, for a maximum period of 5 days.

CONTRA-INDICATIONS:
Pregnancy. Active peptic ulceration.
Sensitivity to naproxen or naproxen sodium formulations. Since the potential exist for cross-sensitivity reactions.

COMPU NAPROXEN 250 should not be given to patients in whom aspirin or other nonsteroidal anti-inflammatory / analgesic medicines induce urticaria, rhinitis or asthma.

WARNINGS:
Serious interaction have been reported after the use of high-dose methotrexate with COMPU NAPROXEN 250.

DOSAGE AND DIRECTIONS FOR USE:
Adults: For rheumatoid arthritis, osteoarthrosis and ankylosing spondylitis, the starting dose and sole maintenance dose is in the range of 500 mg to 1000 mg per day taken in two doses at twelve-hour intervals.
In the following cases a dose of 750 mg or 1 000 mg per day for the acute phase is recommended:

a) in patients reporting severe night-time pain and/or morning stiffness;

b) in patients being switched to COMPU NAPROXEN 250 from a high dose of another antirheumatic compound and,

c) in osteoarthrosis where pain is the predominant symptoms.

For the patients who requires 750 mg per day whose night-time pain and/or morning stiffness are most troublesome, 500 mg should be taken upon retiring and 250 mg upon awakening. For the patients whose day-time pain and reduced mobility are most troublesome, 500 mg should be taken upon awakening and 250 mg upon retiring.

In acute gout, the recommended dosage is 750 mg at once, then 250 mg every eight hours until the attack has passed.

For the treatment of acute musculo-skeletal disorders, the recommended dosage is 250 mg twice or thrice daily; most patients will require only 7 days treatment, but some patients may require up to 14 days treatment.

In dysmenorrhoea, the recommended regime is 500 mg initially, followed by 250 mg every six to eight hours.

Children: For juvenile arthritis in children over 5 years of age the usual dosage is 10 mg per kg body-mass per day in two doses at twelve-hour intervals.

COMPU NAPROXEN 250 is not recommended for use in other indications in children under sixteen years of age.

SIDE-EFFECTS AND SPECIAL PRECAUTIONS:
Episodes of gastro-intestinal bleeding have been reported in patients on COMPU NAPROXEN 250 therapy. COMPU NAPROXEN 250 should be given under close supervision to patients with a history of gastro-intestinal disease.

Due to the high plasma protein binding of COMPU NAPROXEN 250 patients simultaneously receivin g hydantoins, anticoagulants or other highly protein-bound medicines should be observed for signs of potentiation or overdosage of these medicines. Probenecid given concurrently increases COMPU NAPROXEN 250 plasma levels and extent its half life considerably.

Skin rashes, urticaria and angio-oedema have been reported. Patients who have exhibited aspirin sensitivity in the past (usually as the angio-oedema / asthma syndrome) may exhibit the same phenomenon on COMPU NAPROXEN 250. Bronchospasm may be prescipitated in patients suffering from, or with a previous history of bronchial asthma or allergic disease.

The following additional occurences have been reported with COMPU NAPROXEN 250 nausea, vomiting, abdominal discomfort, constipation, epigastric distress, headache, cognitive dysfunction, inability to concentrate, visual disturbances, insomnia, tinnitus and vertigo.

Thrombocytopenia, granulocytopenia, jaundice, aplastic anaemia, haemolytic anaemia, peptic ulceration, reversible renal failure, nephrotic syndrome and nephritis may occur.

Other side-effects include hearing impairment, fatal hepatitis and ulcerative stomatitis, anaphylactic reactions and oesinophilic pneumonitis may occur.

Sporadic abnormalties in laboratory test (eg. liver function tests) have occurred in patients on COMPU NAPROXEN 250 therapy. This effect should be kept in mind when bleeding times are determined.

It is suggested that COMPU NAPROXEN 250 therapy be temporarily discontinued 48 hours before adrenal function tests are performed, because COMPU NAPROXEN 250 may interfere with some assays of urinary 5-hydroxy-indo-leacetic acid.

Mild peripheral oedema has been observed in a few patients receiving COMPU NAPROXEN 250. Although sodium retention has not been reported in metabolic studies, it is possible that patients with questionable or comprised cardiac function may be at greater risk when taking COMPU NAPROXEN 250.

Use in patients with renal impairment:
As naproxen is eliminated to a large extent (95%) by urinary excretion via glomerular filtration it should be used with great caution in patients with impaired renal function and the monitoring of serum creatinine and/or creatinine clearance is advised in these patients. COMPU NAPROXEN 250 is not recommended in patients having baseline clearance less than 20 mL / minute.

Certain patients, specifically those whose renal blood flow is compromised, such as in extracellular volume depletion, cirrhosis of the liver, sodium restriction, congestive heart failure and pre existing renal disease, should have renal function assessed before and during COMPU NAPROXEN 250 therapy. Elderly patients in whom impaired renal function may be expected could also fall within this category. A reduction in daily dosage is recommended to avoid the possibility of excessive accumulation of naproxen metabolites in these patients.

Use in patients with impaired liver function:
Chronic alcoholic liver disease and probably also other forms of cirrhosis reduce the total plasma concentration of naproxen, but the plasma concentration of unbound naproxen is increased. Caution is advised when using COMPU NAPROXEN 250 in patients with hepatic diseases.

Use in the elderly:
Although total plasma concentration of naproxen is unchanged, the unbound plasma fraction of naproxen is increased in the elderly.

Caution is advised and lower doses might be required. COMPU NAPROXEN 250 can reduce the anti-hypertensive effect of propranolol and possibly other beta-blockers.
The natriuretic effect of furosemide has been reported to be inhibited by COMPU NAPROXEN 250.
Inhibition of renal lithium clearance leading to increases in plasma lithium concentration has been reported.
The use of COMPU NAPROXEN 250 should be avoided in patients who are breast-feeding.

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
Significant overdosage of the drug may be characterised by drowsiness, heartburn, indigestion, nausea and vomiting.
Should a patient ingest a large amount of naproxen accidentally or purposefully, the stomach may be emptied and the usual supportive measures employed.

IDENTIFICATION:
250 mg Tablets: Yellow, biconvex, scored tablets.

PRESENTATION:
Securitainers containing 30, 100, 250 and 500 tablets.

STORAGE INSTRUCTIONS:
Store below 25°C and protect from light.
KEEP OUT OF REACH OF CHILDREN.

REGISTRATION NUMBER:
27/3.1/0573

NAME AND BUSINESS ADDRESS OF APPLICANT:
Compu Pharmaceutical Products Limited
476 Kings Highway
Lynwood
Pretoria

DATE AND PUBLICATION OF THIS PACKAGE INSERT:
4 April 1997
SAEPI HOME PAGE TRADE NAME INDEX GENERIC NAME INDEX FEEDBACK
Information presented by Malahyde Information Systems © Copyright 1996-2000

PPT - Drugs for Seizures PowerPoint Presentation

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Drugs for Seizures

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Drugs for Seizures

Epilepsy - Recurrence of Seizures
  • Symptoms depend on type of seizure
  • Include blackout, fainting spells, sensory disturbances, jerking body movements, temporary loss of memory

    Seizures - Disturbances of Electrical Activity in the Brain
    • May affect consciousness, motor activity, sensation
  • Caused by abnormal or uncontrollable neuronal discharges in the brain

  • Electroencephalogram (EEG) measures this activity

  • All seizures are not convulsions

    Convulsions - Involuntary, Violent Spasms of Large Skeletal Muscles
    • Face, neck, arms, and legs
  • All convulsions are seizures

    Anticoagulants Prevent the Formation and Enlargement of Clots
    • Examples - heparin (Heplock), warfarin (Coumadin)
  • Mechanism of action - inhibit specific clotting factors which interfere with coagulation cascade in order to prevent formation or enlargement of clot

  • Primary use - thromboembolic disease; prevent formation of clots in veins

  • Adverse effects - abnormal bleeding

    Antiplatelet Agents Prolong Bleeding Time by Interfering with Platelet Aggregation
    • Example - ticlopidine (Ticlid)
  • Mechanism of actions

    • Aspirin: inhibits thromboxane2, which prevents aggregation of platelets
  • ADP receptor blockers: interfere with platelet plasma membrane, which prevents platelet aggregation

  • Glycoprotein IIb/IIIa inhibitors: glycoprotein IIb/IIIa enzyme inhibited which prevents platelet aggregation

    Thrombolytics Are Used to Dissolve Existing Clots
    • Example - alteplase (Activase)
  • Mechanism of action - convert plasminogen to plasmin which causes fibrin to degrade, then preexisting clot dissolves

  • Primary uses - acute MI, pulmonary embolism, acute ischemic CVA, DVT, arterial thrombosis, coronary thrombosis, clear thrombi in arteriovenous cannulas and blocked IV catheters

  • Adverse effects - abnormal bleeding; contraindicated in patients with active bleeding or recent trauma

    Hemostatics Are Used to Promote the Formation of Clot
    • Example - aminocaproic (Amicar)
  • Mechanism of action - prevent fibrin from dissolving, which enhances stability of the clot

  • Primary use - prevent and treat excessive bleeding from surgical sites

  • Adverse effects - none listed

  • Naprox diseases

    • Product description
    • Safety information
    • Side effects
    • Aleve (naproxen) is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Naproxen works by reducing hormones that cause inflammation and pain in the body. It commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as:

      • osteoarthritis
      • kidney stones
      • rheumatoid arthritis
      • psoriatic arthritis
      • gout
      • ankylosing spondylitis
      • menstrual cramps
      • tendinitis
      • bursitis

      Aleve is commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as:

      • osteoarthritis
      • kidney stones
      • rheumatoid arthritis
      • psoriatic arthritis
      • gout
      • ankylosing spondylitis
      • menstrual cramps
      • tendinitis
      • bursitis

      Take Aleve exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Do not crush, chew, or break an extended-release or enteric-coated tablet. Swallow the pill whole. The extended-release pill is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time. The enteric-coated pill has a special coating to protect your stomach. Breaking the pill could damage this coating. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon.
      If you take Aleve for a long period of time, your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor.

      Since Aleve is sometimes taken only when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time.

      Do not use any other over-the-counter cold, allergy, or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to Aleve (such as ibuprofen or ketoprofen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin, ibuprofen, or ketoprofen. Do not drink alcohol while taking Aleve. Alcohol can increase the risk of stomach bleeding caused by Aleve. Avoid prolonged exposure to sunlight.

      Aleve can make your skin more sensitive to sunlight, and a sunburn may result. Wear protective clothing and use sunscreen (SPF 15 or higher) when you are outdoors.

      Take Aleve exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Do not crush, chew, or break an extended-release or enteric-coated tablet. Swallow the pill whole. The extended-release pill is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time. The enteric-coated pill has a special coating to protect your stomach. Breaking the pill could damage this coating. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon.
      If you take Aleve for a long period of time, your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor.

      Since Aleve is sometimes taken only when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time.

      Do not use any other over-the-counter cold, allergy, or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to Aleve (such as ibuprofen or ketoprofen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin, ibuprofen, or ketoprofen. Do not drink alcohol while taking Aleve. Alcohol can increase the risk of stomach bleeding caused by Aleve. Avoid prolonged exposure to sunlight.

      Aleve can make your skin more sensitive to sunlight, and a sunburn may result. Wear protective clothing and use sunscreen (SPF 15 or higher) when you are outdoors.

      Store Aleve at room temperature away from moisture and heat.

      Before taking Aleve:

      Taking an NSAID can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not use Aleve just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

      NSAIDs can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects.

      Do not use this medication if you are allergic to Aleve, or if you have a history of allergic reaction to aspirin or other NSAIDs.

      If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Aleve:

      • a history of heart attack, stroke, or blood clot;
      • heart disease, congestive heart failure, high blood pressure;
      • a history of stomach ulcers or bleeding;
      • liver or kidney disease;
      • asthma;
      • polyps in your nose;
      • a bleeding or blood clotting disorder; or
      • if you smoke.

      FDA pregnancy category C. Before using Aleve, tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking Aleve during the last 3 months of pregnancy may result in birth defects. Do not take Aleve during pregnancy unless your doctor has told you to. Aleve can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child younger than 2 years old without the advice of a doctor.

      Do not use any other over-the-counter cold, allergy, or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to Aleve (such as ibuprofen or ketoprofen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin, ibuprofen, or ketoprofen. Do not drink alcohol while taking Aleve. Alcohol can increase the risk of stomach bleeding caused by Aleve. Avoid prolonged exposure to sunlight. Aleve may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

      Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking Aleve and seek medical attention or call your doctor at once if you have any of these serious side effects:

      • chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
      • black, bloody, or tarry stools;
      • coughing up blood or vomit that looks like coffee grounds;
      • swelling or rapid weight gain;
      • urinating less than usual or not at all;
      • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
      • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
      • bruising, severe tingling, numbness, pain, muscle weakness; or
      • fever, headache, neck stiffness, chills, increased sensitivity to light, purple spots on the skin, and/or seizure (convulsions).

      Less serious Aleve side effects may include:


    • upset stomach, mild heartburn or stomach pain, diarrhea, constipation;
    • bloating, gas;
    • dizziness, headache, nervousness;
    • skin itching or rash;
    • blurred vision; or
    • ringing in your ears.

      This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

    Customers who bought this product also bought:

    Aspirin Aspirin is in a group of drugs called salicylates. It works by reducing substances in the body that cause pain, fever, and inflammation. as low as $22.85 Benemid Benemid is used to treat gout and gouty arthritis. Benemid is also sometimes given together with penicillin antibiotics to make them more effective. as low as $0.85 Periactin Periactin is used to treat sneezing, itching, watery eyes, runny nose, and other symptoms of allergies. as low as $0.52 Shallaki Shallaki (boswellic acid) is useful in treating arthritis and joint pain. as low as $37 Anacin Anacin is a pain reliever intended for the temporary relief of minor aches and pains. Anacin is a combination salicylate and stimulant. It works by blocking several different chemical processes within the body that cause pain, inflammation, and fever. It also reduces the tendency for blood to clot. as low as $0.48 Toradol Toradol is used short-term (5 days or less) to treat moderate to severe pain, usually after surgery. as low as $0.45

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    Aleve (naproxen) is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Naproxen works by reducing hormones that cause inflammation and pain in the body. It commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as:

    • osteoarthritis
    • kidney stones
    • rheumatoid arthritis
    • psoriatic arthritis
    • gout
    • ankylosing spondylitis
    • menstrual cramps
    • tendinitis
    • bursitis

    Aleve is commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as:

    • osteoarthritis
    • kidney stones
    • rheumatoid arthritis
    • psoriatic arthritis
    • gout
    • ankylosing spondylitis
    • menstrual cramps
    • tendinitis
    • bursitis

    Take Aleve exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Do not crush, chew, or break an extended-release or enteric-coated tablet. Swallow the pill whole. The extended-release pill is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time. The enteric-coated pill has a special coating to protect your stomach. Breaking the pill could damage this coating. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon.
    If you take Aleve for a long period of time, your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor.

    Since Aleve is sometimes taken only when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time.

    Do not use any other over-the-counter cold, allergy, or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to Aleve (such as ibuprofen or ketoprofen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin, ibuprofen, or ketoprofen. Do not drink alcohol while taking Aleve. Alcohol can increase the risk of stomach bleeding caused by Aleve. Avoid prolonged exposure to sunlight.

    Aleve can make your skin more sensitive to sunlight, and a sunburn may result. Wear protective clothing and use sunscreen (SPF 15 or higher) when you are outdoors.

    Store Aleve at room temperature away from moisture and heat.

    Before taking Aleve:

    Taking an NSAID can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not use Aleve just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

    NSAIDs can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects.

    Do not use this medication if you are allergic to Aleve, or if you have a history of allergic reaction to aspirin or other NSAIDs.

    If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Aleve:

    • a history of heart attack, stroke, or blood clot;
    • heart disease, congestive heart failure, high blood pressure;
    • a history of stomach ulcers or bleeding;
    • liver or kidney disease;
    • asthma;
    • polyps in your nose;
    • a bleeding or blood clotting disorder; or
    • if you smoke.

    FDA pregnancy category C. Before using Aleve, tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking Aleve during the last 3 months of pregnancy may result in birth defects. Do not take Aleve during pregnancy unless your doctor has told you to. Aleve can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child younger than 2 years old without the advice of a doctor.

    Do not use any other over-the-counter cold, allergy, or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to Aleve (such as ibuprofen or ketoprofen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin, ibuprofen, or ketoprofen. Do not drink alcohol while taking Aleve. Alcohol can increase the risk of stomach bleeding caused by Aleve. Avoid prolonged exposure to sunlight. Aleve may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

    Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking Aleve and seek medical attention or call your doctor at once if you have any of these serious side effects:

    • chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
    • black, bloody, or tarry stools;
    • coughing up blood or vomit that looks like coffee grounds;
    • swelling or rapid weight gain;
    • urinating less than usual or not at all;
    • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
    • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
    • bruising, severe tingling, numbness, pain, muscle weakness; or
    • fever, headache, neck stiffness, chills, increased sensitivity to light, purple spots on the skin, and/or seizure (convulsions).

    Less serious Aleve side effects may include:


  • upset stomach, mild heartburn or stomach pain, diarrhea, constipation;
  • bloating, gas;
  • dizziness, headache, nervousness;
  • skin itching or rash;
  • blurred vision; or
  • ringing in your ears.

    This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

  • Aleve (Naprox) Delivery

    You can order delivery of a Aleve (Naprox) to the Israel, Norway, Denmark or any other country in the world. Residents of the USA can order Aleve (Naprox) to any city, to any address, for example to Mountain View, Milwaukee, Houston or Cleveland.